Journal of The Korean Society of Clinical Toxicology

Joong-Bum Moon

4 Articles

A Case of Prolonged Coagulopathy in a Patient Intoxicated with Superwarfarin Rodenticide: Chan-Woo Park, Jun-Hwi Cho, Joon-Ho Bae, Joong-Bum Moon, Sung-Bin Chon, Ki-Ohk Ahn, Hui-Young Lee; J Korean Soc Clin Toxicol. 2011;9(2):113-116. Published online December 31, 2011

Abstract PDF: Superwarfarin, such as brodifacoum, is a highly lethal vitamin K antagonist used as a rodenticide. Brodifacoum has a particularly long half-life in the body, which ranges to several months, and therefore requires prolonged treatment with antidotal vitamin K. We experienced a case whereby an 18-year-old male was presented to the hospital with a severe bleeding disorder. It was discovered that he had ingested brodifacoum rodenticide with intent to commit suicide. Despite continual treatment with vitamin K, the bleeding disorder persisted for several months before he recovered. We report this case with literature review.

A Patient with Cellulitis from Intramuscular Glyphosate Injection: Yoon-Sung Kim, Taek-Gun Ohk, Myeung-Cheol Shin, Hyun-Young Choi, Joong-Bum Moon, Sung-Eun Kim, Jeong-Yeul Seo, Moo-Eob Ahn, Byung-Ryul Cho, Yang-Hoon Kim, Bong-Ki Lee, Myeung Kim, Jun-Hwi Cho; J Korean Soc Clin Toxicol. 2007;5(1):71-73. Published online June 30, 2007

Abstract PDF: Glyphosate is the active ingredient in widely used herbicides. It acts through inhibition of the shikimate metabolic pathway in plants. This pathway does not exist in mammals, however, so glyphosate is presumably less toxic to humans. Nevertheless, fatal cases of glyphosate poisoning in humans have still occurred. Cases of glyphosate poisoning reported in the previous literature were almost always caused by intentional ingestion. Therefore, intramuscular injection of glyphosate with suicidal intent has not been reported. We report a case of 43-year-old man with poisoning due to intramuscular injection of glyphosate herbicide. He was admitted to the emergency department with a chilling sensation, local hotness, swelling, and tenderness at the site of glyphosate injection. He was treated with intravenous antibiotics and analgesics for 10 days and was discharged without any other complication.

Two Cases of Rhododendron Brachycarpum Intoxication: Taek-Geun Ohk, Yoon-Seong Kim, Chan-Woo Park, Joong-Bum Moon, Bong-Ki Lee, Byung-Yeul Cho, Yong-Hoon Kim, Seong-Eun Kim, Ki-Hoon Choi, Jeong-Yeul Seo, Hee-Cheol Ahn, Moo-Wob Ahn, Jun-Hwi Cho; J Korean Soc Clin Toxicol. 2006;4(2):143-146. Published online December 31, 2006

Abstract PDF: Historically, the common folk have made use of various wild herbs for both food and medicinal purposes. However, the misuse of these wild herbs can lead to adverse consequences, including severe poisoning in some cases. In cases of poisoning from wild herbs, patients can exhibit a variety of symptoms depending on the herbs involved, which in addition to gastrointestinal symptoms may include hemodynamic alteration and abnormal neurologic signs. In the present case, two patients were admitted to the emergency room with symptoms of toxicity after consuming Rhododendron brachycarpum liquor. Rhododendron brachycarpum and other wild herbs contain the toxic material grayanotoxin. Because of its serious toxic symptoms, great caution must be exercised in using rhododendrons for food and medicinal purposes.

A Patient Presenting with Abnormal Behavior after Wild Plant Ingestion: Taek-Geun Ohk, Yoon-Seong Kim, Chan-Woo Park, Joong-Bum Moon, Ki-Hoon Choi, Jeong-Yeul Seo, Hee-Cheol Ahn, Moo-Wob Ahn, Jun-Hwi Cho; J Korean Soc Clin Toxicol. 2006;4(1):48-51. Published online June 30, 2006

Abstract PDF: With well-being boom recently, the common people, but not experts, are increasingly taking in them directly by picking wild herbs. However, only experts can distinguish between edible vegetables and poisonous herbs from the wild herbs. Especially, it is not even easy for experts to distinguish them only by looking into buds in spring without flowers or fruit. So, sometimes many patients are being carried into the emergency room by the toxic symptom after taking by misunderstanding the poisonous herbs as edible vegetables. For herb intoxication as well as drug intoxication, what kinds of vegetables patients took in, and when and how much they took in them are important information for curing. Of course, in the case of intoxicating in the wild herbs, the patients can have a lot of symptoms and sings-hemodynamic alteration and abnormal neurologic sign as well as gastrointestinal symptoms-according to the kinds of herbs which they took in. Therefore, it is difficult to find the kinds of herbs which they took in through the specific symptoms. Recently we experienced a case with showing typical anticholinergic symptoms after ingestion of Scopolia japonica. As a result, the publicity activities about the wild plants needs because if the person without their previous knowledge take in the poisonous herbs, serious side effects can be produced..

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